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Medical Institute and the National Institutes of Health (R01 DA036858). B.R.C.

received support from the US National Heart, Lung, and Blood Institute, the

National Institutes of Health (U01-HL100406, U01-GM09614, R01-

HL108677, U01-HL098179, U01-HL099997, P01-HL089707, R01HL130533,

and R01-HL060664), and an Agilent University Relations Grant.

Received: August 20, 2015

Revised: December 21, 2015

Accepted: January 24, 2016

Published: March 10, 2016

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